Browsing by Author "Lemos, S"
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- Adenocarcinoma da vagina: caso clínicoPublication . Lemos, S; Dias, M; Silva, T; Oliveira, CF
- Avaliação de uma série de 361 tumores benignos do ovário submetidos a tratamento cirúrgicoPublication . Custódio, S; Lemos, S; Dias, M; Oliveira, CF
- Comportamento evolutivo dos tumores invasivos da mama T2 com base nos factores preditivos clássicosPublication . Custódio, S; Lemos, S; Saleiro, S; Miguéis, J; Dias, M; Rodrigues, V; Oliveira, CF
- Detection of axillary metastases in breast cancer patients using ultrasound and colour Doppler combined with fine needle aspiration cytologyPublication . Lemos, S; Dias, M; Gonçalo, Manuela; Pinto, E; Fernandes, G; Oliveira, CFThe aims of this study were to evaluate the diagnostic value of ultrasonography and colour Doppler combined with fine needle aspiration (FNA) cytology for the detection of non-palpable axillary lymph node metastases in breast cancer patients. Forty patients with operable breast cancer (T1/T2), invasive carcinoma, not submitted to neo-adjuvant therapy, underwent axillary ultrasonography and colour Doppler preoperatively. FNA cytology was performed on axillary lymph nodes presenting ultrasonographic and/or Doppler suspicious features. A total of 542 lymph nodes were surgically removed from the 40 patients; 19 were metastatic lymph nodes. Ultrasound-guided FNA detected metastases in six out of 11 histologically node-positive patients. Sensitivity and specificity in this preliminary study was 55% and 100%, respectively. These are the preliminary results of a prospective study that has the purpose of reducing the sentinel node procedures in breast cancer patients with clinically negative axillae, but positive FNA cytology.
- MÓDULO 2 - Pediatria do Ambulatório IPublication . Bento, C; Rodrigues, F; Oliveira, G; Lopes, MF; Brito, MJ; Canha, J; Oliva, M; Fonseca, P; Soares, R; Lemos, S
- Osteomielite por Serratia e Doença Granulomatosa CrónicaPublication . Campos, M; Rocha, G; Cordeiro, A; Lemos, S; Paiva, A; Silva, I; Faria, EChronic Granulomatous Disease (CGD) is a primary immunodeficiency disorder characterized by recurrent purulent infections of the skin, lungs, and reticuloendothelial organs, primarily due to staphylococci, enteric bacteria, fungi, and occasionally mycobacteria. More than two thirds of all cases are X-linked and result from defects in the CYBB gene that encodes the gp91-phox subunit of NADPH oxidase. The authors present a case of a three month old child admitted with a metacarpic steomyelitis by Serratia marcescens. Studies confirmed an abnormal respiratory burst in activated neutrophils and absence of gp91-phox expression on patient and a brother (with previous Nocardia infection). Both hemizygous for a pathogenic mutation detected in exon 3 of CYBB gene (c.252 G>A, p.Ala84Ala), a variant that affects the splicing. At two years of age he is still on prophylaxis with cotrimoxazol and itraconazol, without relevant complications. CGD is rare but must be evocated in cases of uncommon or atypical infections.
- Tacrolimus Versus Cyclosporine: a study about two immunosuppressive regimensPublication . Lemos, S; Macário, F; Pratas, J; Figueiredo, A; Bastos, C; Mota, A; Campos, M