Browsing by Author "Lemos, C"
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- MÓDULO 3 - Neonatologia e Cuidados Intensivos PediátricosPublication . Brito, C; Rodrigues, F; Oliveira, G; Lopes, MF; Brito, MJ; Farela-Neves, J; Ramos, C; Mesquita, J; Lemos, C; Pinto, C; Dionísio, T; Fonseca, M; Taborda, A; Coelho, L; Dinis, A; Resende, C; Faria, D; Morais, S; Mimoso, G; Dias, A
- Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3Publication . Ribeiro, ML; Alliosio, N; Almeida, H; Gomes, C; Texier, P; Lemos, C; Mimoso, G; Morlé, L; Bey-Cabet, F; Rudigoz, RC; Delaunay, J; Tamagnini, GAbsence of band 3, associated with the mutation Coimbra (V488M) in the homozygous state, caused severe hereditary spherocytosis in a young child. Although prenatal testing was made available to the parents, it was declined. Because the fetus stopped moving near term, an emergency cesarean section was performed and a severely anemic, hydropic female baby was delivered. She was resuscitated and initially kept alive with respiratory assistance and hypertransfusion therapy. Cord blood smears revealed erythroblastosis, poikilocytosis, and red cells with stalk-like elongations. Band 3 and protein 4.2 were absent; spectrin, ankyrin, and glycophorin A were significantly reduced. Renal tubular acidosis was detected by the age of 3 months. Nephrocalcinosis appeared soon thereafter. After 3 years of follow-up the child is doing reasonably well on a regimen that includes regular blood transfusions and daily bicarbonate supplements. The long-term prognosis remains uncertain given the potential for hematologic and renal complications.
- Ventilação não invasiva com pressão positiva intermitente - experiência de 7 anosPublication . Resende, C; Fonseca, M; Mesquita, J; Faria, D; Mimoso, G; Lemos, CIntroduction: Nasal intermittent positive pressure ventilation (NIPPV) is a non invasive ventilation method that combines the benefits of nasal continuous positive airway pressure (NCPAP) and the cycles of positive pressure. Objectives: Description of the NIPPV experience in a neonatal intensive care unit. Methods: A descriptive study of newborns ventilated with NIPPV, from January 2002 to December 2008. Were considered two groups: the first group had mechanical ventilation before NIPPV, and in the second group the initial method was non-invasive ventilation. These 2 groups were subdivided: Group 1: sub-group A, NIPPV immediately after weaning and sub- group B, NIPPV after mechanical ventilation followed by NCPAP. The group 2 was sub-divided in sub-group C, NIPPV after NCPAP, and sub-group D, NIPPV as the initial mode of ventilation. Results: In group 1 we analysed 79 cycles of ventilation with 89% of success and in group 2 55 cycles, with 69% of success. Newborns in group 1 had a median weight of 925g and gestational age of 27 weeks and the group 2 had 1350g and 30 weeks, respectively. Conclusions: NIPPV was used mainly after conventional ventilation in lighter and immature babies, without relevant complications.