Browsing by Issue Date, starting with "1995"
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- Hipersensibilidade ao Timerosal: caracterização da porção sensibilizantePublication . Gonçalo, Margarida; Figueiredo, A; Gonçalo, S
- Endoscopic Nd-YAG laser therapy as palliative treatment for esophageal and cardial cancerPublication . Freitas, D; Gouveia, H; Sofia, C; Pina-Cabral, JE; Donato, ABACKGROUND/AIM: Progressive dysphagia is the most important symptom in inoperable cases of carcinoma of the esophagus and cardia. Treatment for the relief of dysphagia is chosen based on the lowest mortality and morbidity. This paper describes alpha consecutive series of patients with esophageal or cardial cancer, without a documented tracheoesophageal fistula, who were referred for palliative laser therapy. Alternative palliative treatments are discussed, as well as factors involved in successful laser treatment. MATERIAL AND METHODS: Over a five year period, 104 patients were treated endoscopically with the Nd-YAG laser for symptomatic improvement dysphagia caused by malignant tumors of the esophagus or cardia. RESULTS: After the initial laser therapy, good improvement was achieved in 78 patients (75%) and fair improvement in 17 patients (16%). Eighty-three patients with significant improvement were followed until death. In 42 of these 83 patients, the initial laser therapy was the only treatment given; the remaining 41 patients required either additional laser treatment or other palliative therapy. CONCLUSION: Laser treatment for palliation in esophageal and cardial cancer is promising. Given the proper circumstances, it may lay the framework for many other important treatment modalities.
- Reacções à situação de doença no síndrome do hemiplégicoPublication . Oliveira, RA; Laíns, J
- Oral contraceptives and benign breast diseasePublication . Oliveira, CF
- Epilepsia pós-traumática: Conceitos médico-legaisPublication . Barbosa, MD; Costa, G
- Induced pneumoperitoneum in CT evaluation of peritoneal carcinomatosisPublication . Caseiro-Alves, F; Gonçalo, Manuela; Abraúl, E; Pinto, E; Oliveira, CF; Vilaça-Ramos, HBACKGROUND: Imaging of peritoneal carcinomatosis is a well-known problem even for technologies as recent as computed tomography (CT). The purpose of this study was to evaluate whether CT performed after induced pneumoperitoneum (CT-PP) could have a higher sensitivity in the detection of peritoneal implants over conventional CT. METHODS: Five patients with known ovarian malignancies underwent standard CT and CT-PP. Exploratory laparotomy was performed with a maximum interval of 7 days from the last imaging procedure. Results were prospectively compared with surgical findings on a compartment to compartment basis. RESULTS: CT-PP was well-tolerated with no serious adverse reactions registered. The anterior and visceral peritoneum, the paracolic gutters and subphrenic areas were particularly well depicted but not the pelvis which was poorly evaluated in all cases. CT-PP detected all the three cases where peritoneal carcinomatosis was present even when metastatic nodules were smaller than 2 mm; it also showed intraabdominal adhesions in two patients, an important finding that precludes the use of intraperitoneal chemotherapy. CONCLUSIONS: With CT-PP there seems to be a reduction in the threshold of detectability of peritoneal implants. The direct demonstration of intraperitoneal adhesions is an important secondary finding. Disadvantages of CT-PP are (1) it is a time-consuming method and (2) it does not evaluate all the peritoneal recesses potentially involved in peritoneal carcinomatosis.
- Amiloidose primária: Perspectiva terapêuticaPublication . Parente, F; Vieira, JD; Pimenta, P; Alexandrino, MB; Serra e Silva, P
- Breast Cancer: Endocrine therapyPublication . Oliveira, CF
- Terapêutica da hipercalcemia em neoplasias sólidasPublication . Grade, MJ; Parente, F; Alexandrino, MB; Serra e Silva, P