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Browsing by Author "Monteiro, C"

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  • Allergic contact and systemic dermatitis to estradiol
    Publication . Gonçalo, Margarida; Oliveira, HS; Monteiro, C; Clerins, J; Figueiredo, A
    1999Journal article Open access Show more
  • Continuous infusion of piperacillin/tazobactam in septic critically ill patients--a multicenter propensity matched analysis
    Publication . Gonçalves-Pereira, J; Oliveira, BS; Janeiro, S; Estilita, J; Monteiro, C; Salgueiro, A; Vieira, A; Gouveia, J; Paulino, C; Bento, L; Póvoa, P
    The clinical efficacy of continuous infusion of piperacillin/tazobactam in critically ill patients with microbiologically documented infections is currently unknown. We conducted a retrospective multicenter cohort study in 7 Portuguese intensive care units (ICU). We included 569 critically ill adult patients with a documented infection and treated with piperacillin/tazobactam admitted to one of the participating ICU between 2006 and 2010. We successfully matched 173 pairs of patients according to whether they received continuous or conventional intermittent dosing of piperacillin/tazobactam, using a propensity score to adjust for confounding variables. The majority of patients received 16g/day of piperacillin plus 2g/day of tazobactam. The 28-day mortality rate was 28.3% in both groups (p = 1.0). The ICU and in-hospital mortality were also similar either in those receiving continuous infusion or intermittent dosing (23.7% vs. 20.2%, p = 0.512 and 41.6% vs. 40.5%, p = 0.913, respectively). In the subgroup of patients with a Simplified Acute Physiology Score (SAPS) II>42, the 28-day mortality rate was lower in the continuous infusion group (31.4% vs. 35.2%) although not reaching significance (p = 0.66). We concluded that the clinical efficacy of piperacillin/tazobactam in this heterogeneous group of critically ill patients infected with susceptible bacteria was independent of its mode of administration, either continuous infusion or intermittent dosing.
    2012Journal article Open access Show more
  • Sentinel lymph node biopsy for melanoma: experience fo 100 cases
    Publication . Cardoso, R; Vieira, R; Mascarenhas, R; Monteiro, C; Oliveira, H; Freitas, JD; Tellechea, O; Marques, M; Lourenço, C; Duarte, H; Pedroso de Lima, J; Julião, MJ; Figueiredo, A
    2005Journal article Open access Show more
  • Temporal arteritis presenting with scalp ulceration
    Publication . Monteiro, C; Fernandes, B; Reis, JP; Freitas, J; Figueiredo, A
    We report the case of a 75-year-old-woman who presented with bilateral scalp ulcerations and blindness, accompanied by severe headache and scalp tenderness, due to bilateral temporal arteritis without systemic involvement. A biopsy taken from the border of an ulceration showed evidence of giant cell arteritis. She was treated with oral prednisone, 60 mg per day. The ulcerations healed in a few weeks but the vision loss was irreversible. This case highlights for temporal arteritis the importance of accurate and timely diagnosis as well as the need for prompt therapy with systemic steroids in order to avoid major complications, namely loss of vision. It also demonstrates that scalp necrosis and ulcerations are skin signs associated with a poor prognosis.
    2002Journal article Open access Show more