Percorrer por autor "Franco, S"
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- Carcinoma do endométrio em mulheres jovens: a propósito de um caso clínicoPublication . Sousa, R; Silva, T; Carvalho, G; Cortesão, P; Franco, S; Godinho, I; Oliveira, CF
- Carcinoma misto do ovário: a propósito de um caso clínicoPublication . Franco, S; Andrade, MJ; Cortesão, P; Carvalho, G; Sousa, R; Guerra, C; Silva, T; Oliveira, CF
- Efeitos secundários da castração com goserelina em mulheres com cancro da mamaPublication . Franco, S; Lapa, P; Guerra, C; Pereira, L; Oliveira, CFIn the last few years, ovarian ablation with GnRH agonists has been used as first-line adjuvant therapy in pre and perimenopausal breast cancer. These drugs suppress ovarian function in the hypothalamic-pituitary axis and they have adverse effects in other end-organs. A retrospective study was conducted on 35 premenopausal women, with breast cancer, and treated with goserelin, in order to investigate the effects of iatrogenic estrogen suppression. All women complaint of amenorrhea and only half of them referred hot-flashes, weight gain or arthralgias. Hot-flushes and arthralgias remit spontaneously in the end of the treatment. Osteodensitometry was used to access bone mass. There was a reduction in mineral bone mass and T-score at femoral neck and lumbar spine after the treatment with goserelin, but without statistical significance, except for the T-score in lumbar spine.
- História natural da dilatação pielocalicial pré-natalPublication . Franco, S; Carvalho, G; Antunes, A; Brito, M; Morais, C; Barros, JSINTRODUCTION: It is estimated that genitourinary anomalies comprise 20% of all antenatally detected fetal anomalies, and pyelocaliectasia is the most common one. Detection of antenatal dilatation of the urinary tract does not always indicate postnatal urinary tract obstruction or even a significant genitourinary anomaly. Most cases will improve spontaneously, representing a temporary physiologic impedence and do not require surgery. MATERIALS AND METHODS: In a two-year period we studied 197 newborns, with prenatal pyelocaliectasia, without concomitant anomaly, delivered at Maternidade Dr. Daniel de Matos. In the postnatal follow-up period, the infants were followed at Pediatrics Department, at our Center. RESULTS: A male predilection was found. Ultrasonic follow-up of the 197 infants showed that pyelocaliectasia resolved in 97%, while 3% still presented it in the postnatal ultrasound. Complementary renal evaluation, with voiding cystourethrography and radionuclide imaging, was realised in 29 (15%) infants to further characterize the abnormality detected in postnatal ultrasound. Surgery was performed in four (2%) children. CONCLUSION: Prenatally diagnosed pyelocaliectasia may be safely observed, and surgical correction should be performed only if renal compromise occurs.
- Lobulite linfocítica esclerosante: a propósito de um caso clínicoPublication . Carvalho, G; Silva, T; Sousa, R; Franco, S; Cortesão, P; Oliveira, CF
- Tumor desmoide simulando carcinoma da mama: um caso clínicoPublication . Cortesão, P; Andrade, MJ; Franco, S; Carvalho, G; Sousa, R; Silva, T; Torgal, I; Amaral, N; Oliveira, CF
- Tumor uterino semelhante ao tumor dos cordões sexuais do ovárioPublication . Franco, S; Andrade, MJ; Silva, T; Guerra, C; Oliveira, CFUterine tumors resembling ovarian sex-cord tumors are rare and few cases are published in the literature. The authors describe a recently diagnosed one. The clinical features consisted of: abnormal vaginal bleeding and enlargement of the uterus, which allowed confusion with several types of uterine pathology: benign or malignant one; the diagnosis is exclusively histopathological. These tumors have a benign biological behaviour.