Browsing by Author "Costa, G"
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- Aneurismas cerebrais com ruptura: Impacto da cirurgiaPublication . Pereira, R; Gonçalves, J; Costa, G; Cabrita, F; Fernandes, R; Barbosa, MD
- Clinical relevance of incidental colonic uptake 18F-FDG PET/CT. Correlation with colonoscopy and histopathologyPublication . Fernandes, H; Lapa, P; Costa, G; Correia, J; Pedroso de Lima, J
- Detection and Localization of Sentinel Lymph Nodes in Patients with Melanoma. The Added Value of SPECT/CT.Publication . Albuquerque, A; Lapa, P; Moreira, A; Correia, J; Macedo, R; Costa, G; Vieira, R; Figueiredo, A; Pedroso de Lima, J
- Detection of unknown primary tumors using 18F-FDG PET/CTPublication . Fernandes, H; Lapa, P; Costa, G; Correia, J; Pedroso de Lima, J
- Epilepsia pós-traumática: Conceitos médico-legaisPublication . Barbosa, MD; Costa, G
- A fundamental distinction in early neural processing of implicit social interpretation in schizophrenia and bipolar disorderPublication . Madeira, N; Martins, R; Valente Duarte, J; Costa, G; Macedo, A; Castelo-Branco, MBackground: Social cognition impairment is a key phenomenon in serious mental disorders such as schizophrenia (SCZ) and bipolar disorder (BPD). Although genetic and neurobiological studies have suggested common neural correlates, here we hypothesized that a fundamental dissociation of social processing occurs at an early level in these conditions. Methods: Based on the hypothesis that key structures in the social brain, namely the temporoparietal junction, should present distinctive features in SCZ and BPD during low-level social judgment, we conducted a case-control study in SCZ (n = 20) and BPD (n = 20) patients and controls (n = 20), using task-based fMRI during a Theory of Mind (ToM) visual paradigm leading to interpretation of social meaning based on simple geometric figures. Results: We found opposite neural responses in two core ToM regions: SCZ patients showed social content-related deactivation (relative to controls and BPD) of the right supramarginal gyrus, while the opposite pattern was found in BPD; reverse patterns, relative to controls and SCZ, were found in the left posterior superior temporal gyrus, a region involved in inferring other's intentions. Receiver-operating-characteristic curve analysis showed 88% accuracy in discriminating the two clinical groups based on these neural responses. Conclusions: These contrasting activation patterns of the temporoparietal junction in SCZ and BPD represent mechanistic differences of social cognitive dysfunction that may be explored as biomarkers or therapeutic targets.
- Incidental Detection of 18F-FDG Thyroid Uptake: The Risk of MalignancyPublication . Correia, J; Lapa, P; Albuquerque, A; Macedo, R; Silva, R; Fernandes, H; Costa, G; Pedroso de Lima, J
- Mortalidade dos Aneurismas Cerebrais OperadosPublication . Barbosa, MD; Costa, G; Gonçalves, J; Fernandes, R
- Nuclear medicine training and practice in PortugalPublication . Vieira, R; Costa, GNuclear medicine in Portugal has been an autonomous speciality since 1984. In order to obtain the title of Nuclear Medicine Specialist, 5 years of training are necessary. The curriculum is very similar to the one approved under the auspices of the European Union of Medical Specialists, namely concerning the minimum recommended number of diagnostic and therapeutic procedures. There is a final assessment, and during the training the resident is in an approved continuing education programme. Departments are accredited by the Medical College in order to verify their capacity to host nuclear medicine residencies.
- A rapid growing aneurysmPublication . Barbosa, MD; Gonçalves, J; Costa, G; Fernandes, R