Repository logo
 
Publication

Psychological factors associated with response to treatment in rheumatoid arthritis

dc.contributor.authorSantiago, T
dc.contributor.authorGeenen, R
dc.contributor.authorJacobs, JW
dc.contributor.authorPereira da Silva, JA
dc.date.accessioned2016-11-30T11:01:51Z
dc.date.available2016-11-30T11:01:51Z
dc.date.issued2015
dc.description.abstractThis paper presents a comprehensive review of research relating psychological domains with response to therapy in patients with rheumatoid arthritis. A holistic approach to the disease was adopted by incorporating not only disease activity but also dimensions of the impact of disease on patients' lives. Psychological distress, including depression and anxiety, is common among patients with rheumatoid arthritis and has a significant negative impact on response to therapy and on patients' abilities to cope with chronic illness. Evidence regarding the influence of positive psychological dimensions such as acceptance, optimism, and adaptive coping strategies is scarce. The mechanisms involved in these interactions are incompletely understood, although changes in neuro-endocrine-immune pathways, which are common to depression and rheumatoid arthritis, seem to play a central role. Indirect psychological influences on therapeutic efficacy and long-term effectiveness include a myriad of factors such as adherence, placebo effects, cognition, coping strategies, and family and social support. Data suggest that recognition and appropriate management of psychological distress may improve response to treatment and significantly reduce disease burden.pt_PT
dc.identifier.citationCurr Pharm Des. 2015;21(2):257-69.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.4/1984
dc.language.isootherpt_PT
dc.peerreviewedyespt_PT
dc.subjectAnti-Inflamatóriospt_PT
dc.subjectArtrite Reumatóidept_PT
dc.subjectHumanspt_PT
dc.titlePsychological factors associated with response to treatment in rheumatoid arthritispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.startPage257-69pt_PT
oaire.citation.volume21pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Current Pharmaceutical Design.pdf
Size:
1.13 MB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:

Collections