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Bone turnover markers for early detection of fracture healing disturbances: A review of the scientific literature

2015Journal article Open access
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dc.contributor.authorSousa, CP
dc.contributor.authorDias, IR
dc.contributor.authorLopez-Peña, M
dc.contributor.authorCamassa, JA
dc.contributor.authorLourenço, PJ
dc.contributor.authorJudas, F
dc.contributor.authorGomes, ME
dc.contributor.authorReis, RL
dc.date.accessioned2015-09-14T16:05:28Z
dc.date.available2015-09-14T16:05:28Z
dc.date.issued2015
dc.description.abstractImaging techniques are the standard method for assessment of fracture healing processes. However, these methods are perhaps not entirely reliable for early detection of complications, the most frequent of these being delayed union and non-union. A prompt diagnosis of such disorders could prevent prolonged patient distress and disability. Efforts should be directed towards the development of new technologies for improving accuracy in diagnosing complications following bone fractures. The variation in the levels of bone turnover markers (BTMs) have been assessed with regard to there ability to predict impaired fracture healing at an early stage, nevertheless the conclusions of some studies are not consensual. In this article the authors have revised the potential of BTMs as early predictors of prognosis in adult patients presenting traumatic bone fractures but who did not suffer from osteopenia or postmenopausal osteoporosis. The available information from the different studies performed in this field was systematized in order to highlight the most promising BTMs for the assessment of fracture healing outcome.por
dc.identifier.citationAn Acad Bras Cienc. 2015 Apr-Jun;87(2):1049-61.por
dc.identifier.urihttp://hdl.handle.net/10400.4/1833
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectMarcadores Biológicospor
dc.subjectFracturas dos Ossospor
dc.subjectDensidade Ósseapor
dc.titleBone turnover markers for early detection of fracture healing disturbances: A review of the scientific literaturepor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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