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Risk factors for human papillomavirus infection among women in Portugal: the CLEOPATRE Portugal Study

2012-08Journal article Open access
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dc.contributor.authorPista, A
dc.contributor.authorde Oliveira, CF
dc.contributor.authorCunha, MJ
dc.contributor.authorPaixao, MT
dc.contributor.authorReal, O
dc.date.accessioned2019-07-02T14:37:13Z
dc.date.available2019-07-02T14:37:13Z
dc.date.issued2012-08
dc.description.abstractOBJECTIVE: To investigate demographic, socioeconomic, lifestyle, and medical factors that might predispose women to cervical human papillomavirus (HPV) infection. METHOD: A cross-sectional population-based study was performed. Women aged 18-64 years who attended selected obstetrics and gynecology or sexually transmitted disease (STD) clinics in mainland Portugal between February 2008 and March 2009 were recruited, according to an age-stratified sampling strategy. Liquid-based cytology samples were analyzed centrally for HPV genotype and for cytologic features. Univariate and multivariate logistic regression analyses identified risk factors for HPV infection. RESULTS: Among the 2326 women evaluated, the crude prevalence of HPV infection was 19.4%. Lifetime number of sexual partners was a strong predictor of HPV infection (odds ratio 5.44 for 5-10 partners versus 1 partner; P<0.001). Other risk factors were young age (particularly among women aged 20-24 years; P<0.001); country of birth other than mainland Portugal (P=0.002); education up to secondary school level (P=0.010); smoking history (≤ 10 years; P=0.004); and any STD in the past 12 months (P=0.052). CONCLUSION: Data from the present study may aid identification of women at increased risk of HPV infection and target prevention strategies. TRIAL REGISTRATION: National Commission of Data Protection (CNPD) registration number 5346/2007; Sanofi Pasteur MSD study number HPV-E05.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Gynaecol Obstet. 2012 Aug;118(2):112-6.pt_PT
dc.identifier.doi10.1016/j.ijgo.2012.03.028pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.4/2236
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectInfecções por Papillomaviruspt_PT
dc.subjectDoenças do Colo do Úteropt_PT
dc.titleRisk factors for human papillomavirus infection among women in Portugal: the CLEOPATRE Portugal Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage116pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage112-6pt_PT
oaire.citation.volume118pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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