Probable initial pulmonary lymphangioleiomyomatosis and mediastinal lymphangioleiomyoma

Pontes, M; Barbosa, C; Coelho, ML; Carvalho, L

http://hdl.handle.net/10400.4/1599

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Abstract(s)

A 68 year old woman was submitted to a mediastinal lymphangioleiomyoma resection found in a follow-up study of lower left lung resection due to bronchiectasis complicated by chylothorax. This led to a revaluation of the pulmonary specimen that revealed, in addition to inflammatory bronchiectasis, small spindle cell nodules in the lung parenchyma, similar to minute pulmonary meningothelial-like nodules, but with smooth muscle actin immunohistochemical positivity. The possibility of initial pulmonary development of lymphangioleiomyomatosis is discussed.