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European experience on the practical use of levosimendan in patients with acute heart failure syndromes

dc.contributor.authorFollath, F
dc.contributor.authorFranco, F
dc.contributor.authorCardoso, JS
dc.date.accessioned2009-05-21T09:48:35Z
dc.date.available2009-05-21T09:48:35Z
dc.date.issued2005
dc.description.abstractThe novel calcium sensitizer and ATP-dependent potassium channel opener levosimendan has been introduced for routine use in several European countries. Recent reports on clinical experience confirm the positive hemodynamic results and beneficial clinical effects described in the initial dose-finding and randomized comparative therapeutic trials in patients with severe low-output heart failure. In addition, studies in small series of patients with cardiogenic shock after myocardial infarction and/or surgical interventions and post-interventional myocardial dysfunction (stunning) indicate that the inotropic and vasodilating actions of levosimendan may be of value in a wider range of indications. Dose recommendations, combination with other drugs, and potential side effects are discussed in this overview.en
dc.identifier.citationAm J Cardiol. 2005 Sep 19;96(6A):80G-5Gen
dc.identifier.urihttp://hdl.handle.net/10400.4/508
dc.language.isoengen
dc.publisherElsevieren
dc.rights.uriopenAccessen
dc.subjectInsuficiência Cardíacaen
dc.subjectHidrazonasen
dc.subjectPiridazinaen
dc.subjectCardiotónicosen
dc.subjectEuropaen
dc.titleEuropean experience on the practical use of levosimendan in patients with acute heart failure syndromesen
dc.typejournal article
dspace.entity.typePublication
rcaap.typearticleen

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