Publication
Contact allergy to local anaesthetics–value of patch testing with a caine mix in the baseline series
| dc.contributor.author | Brinca, A | |
| dc.contributor.author | Cabral, R | |
| dc.contributor.author | Gonçalo, Margarida | |
| dc.date.accessioned | 2013-06-05T13:28:32Z | |
| dc.date.available | 2013-06-05T13:28:32Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | BACKGROUND: Contact allergy to local anaesthetics is relatively common. Patch testing with benzocaine in the European baseline series is recommended for diagnosis, even though a caine mix has been previously suggested to be superior. OBJECTIVES: To assess the frequency and patterns of contact allergy to local anaesthetics by using a caine mix (benzocaine, tetracaine, and cinchocaine) in the baseline series, and evaluate its efficiency as compared with benzocaine alone. METHODS: We reviewed the results of 2736 patch tests performed between 2000 and 2010, identifying patients with positive reactions to caine mix or to one of seven local anaesthetics. RESULTS: One hundred and twelve patients (4.1%) had at least one allergic reaction to local anaesthetics; 86 were tested with all seven local anaesthetics, resulting in 71 reactions in 53 patients. Cinchocaine gave the most reactions (50.7%); these occurred as a single reaction in 83.3% of patients, mostly with current or past relevance (97%). Benzocaine represented 22.5% of reactions, many of which were non-relevant (44%) or resulting from cross-reactions with para-compounds. CONCLUSIONS: Almost 70% of allergic reactions to local anaesthetics would have been missed if benzocaine had been used as a screening allergen. This study supports a recommendation to replace benzocaine with a caine mix containing cinchocaine in the baseline patch test series. | por |
| dc.identifier.citation | Contact Dermatitis. 2013;68(3):156-62. | por |
| dc.identifier.uri | http://hdl.handle.net/10400.4/1547 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | John Wiley & Sons | por |
| dc.subject | Dermatite de Contacto Alérgica | por |
| dc.subject | Anestésicos Locais | por |
| dc.title | Contact allergy to local anaesthetics–value of patch testing with a caine mix in the baseline series | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |