Browsing by Author "Teixeira, V"
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- [Allergic contact dermatitis to metals over a 20-year period in the Centre of Portugal: evaluation of the effects of the European directives]Publication . Teixeira, V; Coutinho, I; Gonçalo, MargaridaINTRODUCTION: Metals are a common cause of allergic contact dermatitis. After the introduction of the EU Nickel Directive (1994/27/CE; 2004/96/EC) and, more recently, the Cement Directive (2003/53/EC) there has been a significant decrease in sensitization to metals mainly in the Nordic countries. The applicability of these directives and their impact in the Portuguese population is unknown. MATERIAL AND METHODS: A retrospective study (1992-2011) was carried out in our patch test clinic to assess the temporal trend of metal sensitization (nickel [Ni], cobalt [Co] and chromium [Cr]) along the last 20 years, particularly considering age, sex and its relation with occupational activity. RESULTS: Out of 5 250 consecutively patch-tested patients, 1 626 (31%) were reactive to at least one metal (26.5% to Ni; 10.0% to Co and 7.9% to Cr). Women had a higher prevalence of sensitization to Ni (34.4% vs 8.9%) whereas men were more reactive to Cr (11.5% vs 5.0%). Nickel sensitization did not decrease significantly over the years, although in recent years among women sensitized to nickel the percentage of younger patients (16-30 years-old) is significantly lower (p < 0.001). Chromium sensitization significantly decreased, particularly in men (r = -0.535), and mainly in the construction workers (r = -0.639). Chromium reactivity associated with the shoe dermatitis has remained stable. DISCUSSION: We emphasize the higher and stable percentage of nickel sensitized individuals suggesting, so far, a low impact from the EU Ni directive, although a decreasing percentage in the the younger group among Ni sensitized women may suggest a beneficial effect is becoming evident is this age group. On the contrary, the impact of the directive regarding the modification of Cr in cement seems to be effective. There is now a need to regulate chromium content in leather products, namely in shoes. CONCLUSIONS: The regulation of interventional measures related either to the manufacture and trade of adornments or professional use will better protect the population of allergy to metals.
- Do you know this syndrome? Dyspigmentation along the Blaschko lines caused by trisomy 7 mosaicismPublication . Gouveia, MP; Coutinho, I; Teixeira, V; d'Oliveira, R; Venâncio, M; Moreno, ADyspigmentation along the Blaschko lines is strongly suggestive of a mosaic skin disorder. We report a 9-year-old male patient who presented with swirls and streaks of both hypo and hyperpigmentation involving the entire body. Additionally, he had hypertrichosis, musculoskeletal and minor neurodevelopment abnormalities but no intellectual disability. Cultured fibroblast displayed trisomy 7 mosaicism, which can explain this pigmentary phenotype. Widespread dyspigmentation associated with involvement of other organs should prompt systemic examination to detect additional anomalies and genetic evaluation should be considered, even with normal fetal karyotype.
- Hemorragias digestivas altas: cinco anos de experiência do Serviço de Gastrenterologia dos Hospitais da Universidade de CoimbraPublication . Sofia, C; Donato, A; Leitão, M; Gouveia, H; Oliveira, MG; Pimenta, I; Romãozinho, JM; Cantante, J; Chaves, A; Dias, A; Pinto, G; Baptista, E; Ganho, E; Júlio, M; Teixeira, V; Domingos, J; Moules, J; Bilhau, J; Arruda, F; Barbosa, J; Freitas, D; Gouveia-Monteiro, J
- A large pigmented lesion mimicking malignant melanomaPublication . Brinca, A; Teixeira, V; Gonçalo, Margarida; Tellechea, O
- Melanoma: when dermoscopy is a pitfallPublication . Teixeira, V; Serra, D; Vieira, R; Figueiredo, A; Julião, MJ
- Melanoma: when dermoscopy is a pitfallPublication . Teixeira, V; Serra, D; Vieira, R; Figueiredo, A; Julião, MJ
- Reninoma: uma causa rara de hipertensão arterialPublication . Pina, R; Barbosa, B; Morales, J; Correia, J; Teixeira, V; Furtado, AL; Saldanha, MH