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Obstetrícia

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Browsing Obstetrícia by Author "Almeida, MC"

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  • Crise hipercalcémia secundária a hiperparatiroidismo primário durante a gravidez
    Publication . Branco, MR; Rodrigues, CT; Campos, A; Figueiredo, A; Coucelo, J; Magalhães, C; Santos-Silva, I; Taborda, A; Almeida, MC
    Primary hyperparathyroidism is a rare occurrence in pregnancy with significant risks to the mother and the foetus, witch is related to the level of serum calcium. A 41-year-old women, gravida 2, para 1, presented at 22 weeks gestation with nausea, vomiting and mild cognitive dysfunction associated with hypercalcemic crisis. The hypercalcemia was observed to be related to parathyroid hyperplasia that was surgically removed. Complete resolution of her symptomatology and hypercalcemia occurred postoperatively. The pregnancy was complicated with transient hypertension. A small for gestational age healthy male infant was delivered at term with no neonatal complications related with this pathology.
    2005Journal article Open access Show more
  • Epidemiologia da gestação múltipla: casuística de 15 anos
    Publication . Rodrigues, CT; Branco, MR; Ferreira, ID; Nordeste, A; Fonseca, M; Taborda, A; Santos-Silva, I; Almeida, MC
    Between January of 1987 and December of 2001 were born 1243 twins related to 609 multiple pregnancies, in Maternidade Bissaya-Barreto. Data were grouped in periods of three years and several parameters were studied. The rate of multiple gestation has increased probably due to the contribution of the assisted conception techniques, and to the increase of the number of multiple fetal pregnancies (two or more) and to the increase of the mother age. These more frequent obstetric problems were preterm birth, gestational hypertension and abnormal sonographic data of fetal growth. The average age of delivery was 34 weeks and the birth weight has decreased. The most important factors for neonatal morbidity were hyaline membranous disease, intraventricular haemorrhage and the twin-twin transfusion syndrome. The neonatal mortality decreased in the last studied period.
    2005Journal article Open access Show more
  • 2010Journal article Open access Show more
  • Newborn Urinary Metabolic Signatures of Prematurity and Other Disorders: A Case Control Study
    Publication . Diaz, SO; Pinto, JJ; Barros, AS; Morais, E; Duarte, D; Negrão, F; Pita, C; Almeida, MC; Carreira, IM; Spraul, M; Gil, AM
    This work assesses the urinary metabolite signature of prematurity in newborns by nuclear magnetic resonance (NMR) spectroscopy, while establishing the role of possible confounders and signature specificity, through comparison to other disorders. Gender and delivery mode are shown to impact importantly on newborn urine composition, their analysis pointing out at specific metabolite variations requiring consideration in unmatched subject groups. Premature newborns are, however, characterized by a stronger signature of varying metabolites, suggestive of disturbances in nucleotide metabolism, lung surfactants biosynthesis and renal function, along with enhancement of tricarboxylic acid (TCA) cycle activity, fatty acids oxidation, and oxidative stress. Comparison with other abnormal conditions (respiratory depression episode, large for gestational age, malformations, jaundice and premature rupture of membranes) reveals that such signature seems to be largely specific of preterm newborns, showing that NMR metabolomics can retrieve particular disorder effects, as well as general stress effects. These results provide valuable novel information on the metabolic impact of prematurity, contributing to the better understanding of its effects on the newborn's state of health.
    2016-01-04Journal article Open access Show more
  • Taquicardia supra-ventricular fetal: 15 anos de experiência
    Publication . Santos-Silva, I; Almeida, MC; Cruz, A; Nordeste, A; Mimoso, G; Castela, E; Mesquita, J
    2008Journal article Open access Show more