Couto, MDuarte, CGeraldes, AMedeiros, CInês, LMalcata, AB2009-11-242009-11-242009Acta Reumatol Port. 2009 Jul-Sep;34(3):526-30.http://hdl.handle.net/10400.4/702We report a case of severe type IV hypersensitivity reaction to amoxicillin, which occurred in a person with a 12-year history of SLE. The present case illustrates the wide differential diagnosis in a SLE patient who presents with an allergic drug reaction. The attribution of the presenting symptoms to the underlying SLE and/or to the drugs used to treat SLE and coexisting conditions is a major challenge.engLúpus Eritematoso SistémicoAmoxicilinajournal article