Duarte, CCouto, MInês, LMalcata, AB2008-12-112008-12-112007Acta Reumatol Port. 2007 Apr-Jun;32(2):175-80http://hdl.handle.net/10400.4/327Systemic Lupus Erythematosus (SLE) is a rheumatic autoimmune disease characterized by multisystemic involvement with a variable prognosis. The association with Antiphospholipid Syndrome (APS) occurs in about 36% of the patients, raising additional problems with treatment and monitoring of these patients. The authors report a clinical case of a girl with SLE and APS who represented Budd-Chiari Syndrome and severe thrombocytopenia. The patient had severe thrombotic event and simultaneously a high hemorrhagic risk due to thrombocytopenia. Long-term resolution of the thrombocytopenia was achieved with mycophenolate mofetil. Long-term anticoagulation for thrombosis prophylaxis is requiredporLúpus Eritematoso SistémicoSíndrome AntifosfolipídicoSíndrome de Budd-ChiariTrombocitopeniajournal article