Moura, ALPereira, CRegateiro, FSAzevedo, JTodo Bom, ACarrapatoso, I2024-02-202024-02-202019Eur Ann Allergy Clin Immunol . 2019 Sep 16;51(5):206-212.http://hdl.handle.net/10400.4/2354Introduction. Sublingual immunotherapy (SLIT) with Pru p 3 can prevent severe allergic reactions to LTP-containing foods, but the standard initiation protocol is time-consuming. Objectives. Establish the safety of a novel ultra-rush initiation protocol for SLIT with Pru p 3. Methods. Prospective study comparing the side effects of the standard vs novel ultra-rush initiation protocols of SLIT with Pru p 3 in patients with anaphylaxis to LTP. Results. Fifteen patients were included (standard initiation, 5; ultra-rush initiation, 10), 80% females. All patients had oropharyngeal pruritus during initiation, 80% with spontaneous recovery, but no other gastro-intestinal, respiratory, cutaneous or systemic side effects occurred in any patient of both groups. Conclusion. The novel ultra-rush protocol halved the build-up time without increasing side effects.engHipersensibilidade AlimentarImunoterapia Sublingualjournal article10.23822/EurAnnACI.1764-1489.99