Lemos, MCCoutinho, EGomes, LBastos, MFagulha, ABarros, LCarrilho, FGeraldes, ERegateiro, FJCarvalheiro, M2009-09-182009-09-182009Int J Immunogenet. 2009 Jun;36(3):193-5.http://hdl.handle.net/10400.4/656CTLA4 genetic polymorphisms have been associated with type 1 diabetes. We genotyped 207 patients and 249 controls for the most frequently investigated polymorphism of the CTLA4 gene (+49A/G (rs231775)). No significant differences were observed, suggesting that this polymorphism is not strongly associated with type 1 diabetes in the Portuguese population.engDiabetes Mellitus Tipo 1Antigénio CDPredisposição Genética para DoençaThe CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 diabetes mellitus in the Portuguese populationjournal article