Brás, JMGuerreiro, RJRibeiro, MHJanuário, CMorgadinho, AOliveira, CRHardy, JSingleton, A2009-02-182009-02-182005Mov Disord. 2005 Dec;20(12):1653-5http://hdl.handle.net/10400.4/464LRRK2 mutations have recently been described in families with Parkinson's disease. Here we show that one of them (G2019S) is present in 6% (7 of 124) unrelated cases of disease in a clinic-based sample series from central Portugal, but not present in 126 controls from the same population. Thus, LRRK2 mutations appear to be a common cause of typical Parkinson's disease and as such will alter clinical practice.engPredisposição Genética para DoençaDoença de ParkinsonMutaçãojournal article