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Organizing pneumonia due to actinomycosis: an undescribed association

dc.contributor.authorAlfaro, TM
dc.contributor.authorBernardo, J
dc.contributor.authorGarcia, H
dc.contributor.authorAlves, F
dc.contributor.authorCarvalho, L
dc.contributor.authorCaseiro-Alves, F
dc.contributor.authorRobalo-Cordeiro, C
dc.date.accessioned2012-02-28T14:50:41Z
dc.date.available2012-02-28T14:50:41Z
dc.date.issued2011
dc.description.abstractOrganizing pneumonia is a pathologic entity characterized by intra-alveolar buds of granulation tissue that can extend to the bronchiolar lumen. It is a non-specific finding reflecting a pattern of pulmonary response to aggression that can be cryptogenic or associated with several causes. Pulmonary actinomycosis is a rare infectious disease, of bacterial aetiology, and of difficult diagnosis. This disease usually causes non-specific respiratory symptoms and radiological findings, and the treatment is based on the use of antibiotics. The authors describe a clinical case of a 53-year-old male smoker (50 pack years), initially seen for complaints of right-sided chest pain and sub-febrile temperature. Imaging studies revealed a mass in the inferior right lobe and enlarged mediastinal lymph nodes. Empirical treatment with antibiotics caused partial and temporary improvement. Transthoracic biopsy revealed a pattern of organizing pneumonia with giant multinucleated cell granulomas. Repeat imaging studies revealed an enlargement of the pulmonary mass and therefore a right inferior lobectomy was performed. The pathologic study revealed a histological pattern of organizing pneumonia surrounding inflammatory bronchiectasis with a large number of Actinomyces colonies. To our knowledge there is presently no report in the literature of organizing pneumonia associated with Actinomyces infection.por
dc.identifier.citationRespiration. 2011;81(5):433-6.por
dc.identifier.urihttp://hdl.handle.net/10400.4/1314
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherKargerpor
dc.subjectActinomicosepor
dc.subjectDoenças do Pulmãopor
dc.subjectPneumonia Organizativa Criptogénicapor
dc.titleOrganizing pneumonia due to actinomycosis: an undescribed associationpor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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