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Brucelose osteo-articular: um retrato dos Ășltimos 10 anos

dc.contributor.authorSantiago, T
dc.contributor.authorRovisco, J
dc.contributor.authorSilva, J
dc.contributor.authorPereira da Silva, JA
dc.date.accessioned2011-11-21T12:47:20Z
dc.date.available2011-11-21T12:47:20Z
dc.date.issued2011
dc.description.abstractOBJECTIVES: Characterize Osteoarticular Brucellosis in the University Hospital of Coimbra (HUC) in the past decade. MATERIAL AND METHODS: A retrospective study of the cases diagnosed between January/2000 and December/2009 in the HUC. RESULTS: Ninety patients were admitted with the dia-gnosis of brucellosis in our hospital, of whom 44 (49%; 18 men; 26 women, mean 49.5 years) had osteoarticular complications. Twenty-five (45%) patients had a positive epidemiological context. The most frequent clinical manifestation was local pain (73%) followed by polyarthralgias and constitutional symptoms. The C-reactive protein was the inflammatory marker most often increased (82%). The Rose Bengala test was positive in 42 patients, and a Wright's sero-aglutination above than 1/160 was detected in 28 patients. An etiologic agent was isolated in 28 (64%) patients, with 70% of positive blood cultures. The imaging procedure of choice was magnetic resonance imaging (MRI) (46%). The osteo-articular manifestation most frequent was spondylodiscitis (57%) with a lumbosacral involvement in 40%. All patients completed antibiotic therapy. One patient underwent surgery to drain the abscess. Patients had an average length of admission of 28.3 days, with a good outcome in 60%, and a reasonable outcome in 20%, despite 20% of the patients lost follow-up. CONCLUSIONS: Brucellosis is a disease of obligatory declaration not eradicated in Portugal, with a great impact on socio-economic and public health. So, this epidemiological knowledge of brucellosis cases, allows an early intervention and therapy.por
dc.identifier.citationActa Reumatol Port. 2011 Apr-Jun;36(2):120-5.por
dc.identifier.urihttp://hdl.handle.net/10400.4/1165
dc.language.isoporpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Reumatologiapor
dc.subjectBrucelosepor
dc.subjectArtrite Infecciosapor
dc.titleBrucelose osteo-articular: um retrato dos Ășltimos 10 anospor
dc.title.alternativeOsteoarticular brucellosis: an analysis of the past decadepor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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