Instability of misoprostol tablets stored outside the blister: a potential serious concern for clinical outcome in medical abortion

Berard, V; Fiala, C; Cameron, S; Bombas, T; Parachini, M; Gemzell-Danielsson, K

http://hdl.handle.net/10400.4/1990

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Authors

Gemzell-Danielsson, K

Abstract(s)

Misoprostol (Cytotec) is recognised to be effective for many gynaecological indications including termination of pregnancy, management of miscarriage and postpartum haemorrhage. Although not licensed for such indications, it has been used for these purposes by millions of women throughout the world. Misoprostol tablets are most often packaged as multiple tablets within an aluminium strip, each within an individual alveolus. When an alveolus is opened, tablets will be exposed to atmospheric conditions.