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Visual Cortex Plasticity Following Peripheral Damage To The Visual System: fMRI Evidence

dc.contributor.authorLemos, J
dc.contributor.authorPereira, D
dc.contributor.authorCastelo-Branco, M
dc.date.accessioned2018-06-20T15:33:40Z
dc.date.available2018-06-20T15:33:40Z
dc.date.issued2016
dc.description.abstractOver the last two decades, functional magnetic resonance imaging (fMRI) has become a powerful research method to investigate cortical visual plasticity. Abnormal fMRI response patterns have been occasionally detected in the visually deprived cortex of patients with bilateral retinal diseases. Controversy remains whether these observations indicate structural reorganization of the visual cortex or unmasking of previously silent cortico-cortical connections. In optic nerve diseases, there is weak evidence showing that early visual cortex seems to lack reorganization, while higher-order visual areas undergo plastic changes which may contribute to optimise visual function. There is however accumulating imaging evidence demonstrating trans-synaptic degeneration of the visual cortex in patients with disease of the anterior visual pathways. This may preclude the use of restorative treatments in these patients. Here, we review and update the body of fMRI evidence on visual cortical plasticity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCurr Neurol Neurosci Rep. 2016 Oct;16(10):89.pt_PT
dc.identifier.doi10.1007/s11910-016-0691-0pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.4/2150
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectRessonância Magnéticapt_PT
dc.subjectDoenças da Retinapt_PT
dc.subjectCórtex Visualpt_PT
dc.titleVisual Cortex Plasticity Following Peripheral Damage To The Visual System: fMRI Evidencept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue10pt_PT
oaire.citation.startPage89pt_PT
oaire.citation.volume16pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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