Donor mitral valve repair in cardiac transplantation

Prieto, D; Antunes, PE; Antunes, MJ

Publication

Donor mitral valve repair in cardiac transplantation

2009Journal article

dc.contributor.author	Prieto, D
dc.contributor.author	Antunes, PE
dc.contributor.author	Antunes, MJ
dc.date.accessioned	2009-06-09T15:55:57Z
dc.date.available	2009-06-09T15:55:57Z
dc.date.issued	2009
dc.description.abstract	INTRODUCTION: For many patients suffering from end-stage heart failure, heart transplantation remains the only hope for survival, but the shortage of donor organ is increasing. The growing number of patients awaiting heart transplantation has led many centers to expand the donor pool by liberalizing donor criteria, including advances in surgical techniques on the donor heart, such as valve repair. PATIENTS AND RESULTS: We subjected 4 donor hearts to bench repair of the mitral valve. The first heart was from a 35-year-old woman whose echocardiogram showed mild to moderate sclerotic leaflets. We performed a posteromedial commissurotomy and posterior annuloplasty. Transthoracic echocardiography at 57 months after transplantation demonstrated mild mitral regurgitation and no enlargement of VE. The second organ was from a 17-year-old woman with no history of heart disease and an echocardiogram that showed evidence of slightly sclerotic leaflets and mild mitral regurgitation. We performed a posterior annuloplasty. Echocardiography at 12 months demonstrated minimal mitral regurgitation. The third heart was from a 28-year-old woman with a normal echocardiogram. After harvesting, we found a torn head of the posterior papillary muscle, which was reimplanted. Two weeks later, the echocardiogram showed no mitral regurgitation. The fourth was from a 47-year-old woman with no history of heart disease and a normal echocardiogram. Examination before implantation showed central insufficiency, for which we performed posterior annuloplasty. Echocardiography at 12 months showed no mitral regurgitation. CONCLUSION: An aggressive approach to use hearts from marginal donors expands the pool and decreases waiting time for patients who desire heart transplantation.	en
dc.identifier.citation	Transplant Proc. 2009 Apr;41(3):932-4.	en
dc.identifier.uri	http://hdl.handle.net/10400.4/531
dc.language.iso	eng	en
dc.publisher	Elsevier	en
dc.rights.uri	openAccess	en
dc.subject	Insuficiência da Válvula Mitral	en
dc.subject	Estenose da Válvula Mitral	en
dc.subject	Procedimentos Cirúrgicos Cardíacos	en
dc.subject	Transplantação de Coração	en
dc.title	Donor mitral valve repair in cardiac transplantation	en
dc.type	journal article
dspace.entity.type	Publication
rcaap.type	article	en