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Oral squamous cell carcinoma: review of prognostic and predictive factors

dc.contributor.authorMassano, J
dc.contributor.authorRegateiro, FS
dc.contributor.authorJanuário, G
dc.contributor.authorFerreira, A
dc.date.accessioned2008-11-20T15:37:21Z
dc.date.available2008-11-20T15:37:21Z
dc.date.issued2006
dc.description.abstractOral squamous cell carcinoma has a remarkable incidence worldwide and a fairly onerous prognosis, encouraging further research on factors that might modify disease outcome. In this review article, the authors approach the factors that may exert influence on the prognosis and eventually guide the selection of patients for more aggressive therapies. Published scientific data was collected, selected, and grouped into 3 main clusters: patient-, tumor-, and treatment-related factors. Well established aspects are discussed, but also those less common or with only supposed usefulness. Disease staging, extracapsular dissemination, resection margin free of disease, and tumor thickness are factors with high influence on the prognosis. There has been an increasing interest in the study of tumor molecular factors, and some have been strongly correlated with the outcome, showing promising pathways for the future development of more effective prognosis systems and anticancer therapies.en
dc.identifier.citationOral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jul;102(1):67-76en
dc.identifier.urihttp://hdl.handle.net/10400.4/96
dc.language.isoengen
dc.publisherElsevieren
dc.rights.uriopenAccessen
dc.subjectCarcinoma de Células Escamosasen
dc.subjectMarcadores Tumorais Biológicosen
dc.subjectNeoplasias da Bocaen
dc.titleOral squamous cell carcinoma: review of prognostic and predictive factorsen
dc.typejournal article
dspace.entity.typePublication
rcaap.typearticleen

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