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Physicochemical characterization of biomaterials commonly used in dentistry as bone substitutes--comparison with human bone

dc.contributor.authorFigueiredo, M
dc.contributor.authorHenriques, J
dc.contributor.authorMartins, G
dc.contributor.authorGuerra, F
dc.contributor.authorJudas, F
dc.contributor.authorFigueiredo, H
dc.date.accessioned2011-12-22T11:40:24Z
dc.date.available2011-12-22T11:40:24Z
dc.date.issued2010
dc.description.abstractThe present work focuses on the physicochemical characterization of selected mineral-based biomaterials that are frequently used in dental applications. The selected materials are commercially available as granules from different biological origins: bovine, porcine, and coralline. Natural and calcined human bone were used for comparison purposes. Besides a classical rationalization of chemical composition and crystallinity, a major emphasis was placed on the measurement of various morphostructural properties such as particle size, porosity, density, and specific surface area. Such properties are crucial to acquiring a full interpretation of the in vivo performance. The studied samples exhibited distinct particle sizes (between 200 and 1000 microm) and shapes. Mercury intrusion revealed not only that the total sample porosity varied considerably (33% for OsteoBiol, 50% for PepGen P-15, and 60% for BioOss) but also that a significant percentage of that porosity corresponded to submicron pores. Biocoral was not analyzed by this technique as it possesses larger pores than those of the porosimeter upper limit. The density values determined for the calcined samples were close to the theoretical values of hydroxyapatite. However, the values for the collagenated samples were lower, in accordance with their lower mineral content. The specific surface areas ranged from less than 1 m(2)/g (Biocoral) up to 60 m(2)/g (BioOss). The chemical and phase composition of most of the samples, the exception being Biocoral (aragonite), were hydroxyapatite based. Nonetheless, the samples exhibited different organic material content as a consequence of the distinct heat treatments that each had received.por
dc.identifier.citationJ Biomed Mater Res B Appl Biomater. 2010;92(2):409-19.por
dc.identifier.urihttp://hdl.handle.net/10400.4/1214
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherWileypor
dc.subjectMateriais Biocompatíveispor
dc.subjectSubstitutos do Ossopor
dc.titlePhysicochemical characterization of biomaterials commonly used in dentistry as bone substitutes--comparison with human bonepor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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