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Can we improve outcomes in patients with previous coronary artery bypass surgery admitted for acute coronary syndrome?

2010Journal article Open access
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dc.contributor.authorTeixeira, R
dc.contributor.authorLourenço, C
dc.contributor.authorAntónio, N
dc.contributor.authorJorge, E
dc.contributor.authorBaptista, R
dc.contributor.authorSaraiva, F
dc.contributor.authorMendes, P
dc.contributor.authorMonteiro, S
dc.contributor.authorGonçalves, F
dc.contributor.authorMonteiro, P
dc.contributor.authorFreitas, M
dc.contributor.authorProvidência, LA
dc.date.accessioned2010-06-24T11:38:09Z
dc.date.available2010-06-24T11:38:09Z
dc.date.issued2010
dc.description.abstractINTRODUCTION AND OBJECTIVES: Prognosis and in-hospital management of patients with acute coronary syndrome (ACS) and a history of coronary artery bypass graft (CABG) surgery are still debated. The objective of this study was to characterize ACS patients with a CABG and to compare their in-hospital and postdischarge outcomes with those of patients without a CABG. METHODS: This ongoing prospective observational study included 1,495 consecutive patients admitted for ACS to a coronary care unit and followed up for a mean of 19 months. There were two groups: group A (n=73), with CABGs; and group B (n=1,223), without CABGs. RESULTS: Group A patients were more often male (86.3% versus 69.1%; P=.002), and more frequently had a history of diabetes, myocardial infarction and heart failure. Group B patients more frequently had ST-elevation myocardial infarction, and had a higher median ejection fraction (53% [interquartile range, 47%-60%] vs. 50% [42%-55%]; P< .01) and peak troponin-I concentration. There was no difference in the use of invasive techniques. Regarding medication, Group B patients were more likely to receive dual antiplatelet therapy at discharge. No significant difference was observed in in-hospital mortality (9.5% versus 5.9%; P=.2) or mortality at 1 month, 6 months or 1 year (9.8% versus 9.1%; log-rank test, P=.87) and the cumulative major adverse cardiac event rate was equally low in both groups. The presence of a CABG was associated with more readmissions for unstable angina (11.3% vs. 3.1%; P< .01). CONCLUSIONS: In our ACS patients, the presence of a CABG had no significant influence on short- or medium-term outcomes, such as all-cause mortality and adverse cardiac events.pt
dc.identifier.citationRev Esp Cardiol. 2010 May;63(5):554-63.pt
dc.identifier.urihttp://hdl.handle.net/10400.4/791
dc.language.isoengpt
dc.subjectBypass da Artéria Coronáriapt
dc.subjectDoença Coronáriapt
dc.titleCan we improve outcomes in patients with previous coronary artery bypass surgery admitted for acute coronary syndrome?pt
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspt
rcaap.typearticlept

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