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Nicolau Livedoid Dermatitis following intramuscular benzathine penicillin injection

dc.contributor.authorAndrade, P
dc.contributor.authorPereira, N
dc.contributor.authorBrites, MM
dc.contributor.authorGonçalo, Margarida
dc.contributor.authorFigueiredo, A
dc.date.accessioned2011-01-06T16:03:08Z
dc.date.available2011-01-06T16:03:08Z
dc.date.issued2010
dc.description.abstractWe report the case of a 64-year-old male presenting with a rapidly enlarging painful violaceous plaque in the left buttock and posterior thigh, following a gluteal intramuscular injection of benzathine penicillin. Associated urinary incontinence and lower left limb paresis were consistent with sciatic and lower sacral nerve damage, as confirmed by electromyography. Additional underlying muscular damage was observed in ultrasound and computer tomodensitometry scans and supported by high serum levels of creatine kinase and lactate dehydrogenase. Aggressive treatment was performed with fluid expansion, intravenous steroid bolus, vasodilators and anticoagulation, resulting in slow improvement of cutaneous and muscular lesions. However, no significant effect was observed on neurologic dysfunction after 6 months of regular neuromuscular rehabilitation. Nicolau Livedoid Dermatitis is a rare and potentially fatal condition showing variable levels of tissue impairment and unpredictable course and prognosis. Specific treatment is not consensual and the efficacy of any particular treatment remains to be established.por
dc.identifier.citationDermatol Online J. 2010 Dec 15;16(12):11.por
dc.identifier.urihttp://hdl.handle.net/10400.4/931
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectDoenças da Pelepor
dc.subjectPenicilina G Benzatinapor
dc.titleNicolau Livedoid Dermatitis following intramuscular benzathine penicillin injectionpor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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