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Drug-Induced Anaphylaxis: An Update on Epidemiology and Risk Factors

dc.contributor.authorRegateiro, FS
dc.contributor.authorMarques, ML
dc.contributor.authorGomes, ER
dc.date.accessioned2024-06-05T12:06:11Z
dc.date.available2024-06-05T12:06:11Z
dc.date.issued2020
dc.description.abstractDrug hypersensitivity is one of the most frequent causes of anaphylaxis, particularly in adults and in hospitalized patients. Drug-induced anaphylaxis (DIA) is also associated with more severe outcomes than other anaphylaxis triggers, and drugs are responsible for the majority of deaths due to anaphylaxis. We here review the current knowledge on the incidence, prevalence, drugs involved, mortality, and mortality risk factors for DIA. The incidence of both anaphylaxis and DIA seems to be increasing worldwide. Antibiotics and analgesics are the most frequently reported triggers of DIA. However, the importance of other drug groups should be taken into account, especially in particular settings (e.g., peri-operative and oncology). The identification of risk factors, geographical variables, and drugs associated with higher risk for DIA may improve the outcomes of this entity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt Arch Allergy Immunol . 2020;181(7):481-487.pt_PT
dc.identifier.doi10.1159/000507445pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.4/2355
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectAnafilaxia/induzida quimicamentept_PT
dc.subjectHipersensibilidade a Medicamentospt_PT
dc.titleDrug-Induced Anaphylaxis: An Update on Epidemiology and Risk Factorspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage487pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage481pt_PT
oaire.citation.titleInternational Archives of Allergy and Immunologypt_PT
oaire.citation.volume181pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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