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The CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 diabetes mellitus in the Portuguese population
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Orientador(es)
Resumo(s)
CTLA4 genetic polymorphisms have been associated with type 1 diabetes. We genotyped 207 patients and 249 controls for the most frequently investigated polymorphism of the CTLA4 gene (+49A/G (rs231775)). No significant differences were observed, suggesting that this polymorphism is not strongly associated with type 1 diabetes in the Portuguese population.
Descrição
Palavras-chave
Diabetes Mellitus Tipo 1 Antigénio CD Predisposição Genética para Doença
Contexto Educativo
Citação
Int J Immunogenet. 2009 Jun;36(3):193-5.