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Extensive intracranial involvement with multiple dissections in a case of giant cell arteritis

dc.contributor.authorParra, J
dc.contributor.authorDomingues, J
dc.contributor.authorSargento-Freitas, J
dc.contributor.authorSantana, I
dc.date.accessioned2014-04-17T14:43:14Z
dc.date.available2014-04-17T14:43:14Z
dc.date.issued2014
dc.description.abstractA 56-year-old man presented with weight loss, articular pain and minor neurological symptoms progressing over 1 month. Neurosonological evaluation suggested occlusion in intracranial segments of the left vertebral artery (VA) and of both internal carotid arteries (ICA) and hypoechoic halo sign in both superficial temporal arteries. The diagnosis of giant cell arteritis was supported by inflammatory markers and confirmed by biopsy. Despite early steroid initiation, he manifested fluctuant vascular deficits and became lethargic. Brain MRI indicated watershed infarcts and intracranial dissections of left VA and both ICA. The patient was stabilised with the association of prednisolone 2 mg/kg, methotrexate and oral anticoagulation. Since then he has been neurologically asymptomatic and control imaging showed only residual intracranial left VA stenosis, with no signs of temporal artery inflammation or new vascular lesions. This is to the best of our knowledge, the first reported clinical case with such an extensive intracranial involvement with multiple dissections.por
dc.identifier.citationBMJ Case Rep. 2014 Apr 11;2014. pii: bcr2014204130.por
dc.identifier.urihttp://hdl.handle.net/10400.4/1680
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherBMJpor
dc.subjectArterite de Células Gigantespor
dc.subjectNeoplasias Cerebraispor
dc.titleExtensive intracranial involvement with multiple dissections in a case of giant cell arteritispor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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