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Allergic contact dermatitis to shoes induced by dimethylfumarate: A new allergen imported from China

dc.contributor.authorSantiago, F
dc.contributor.authorAndrade, P
dc.contributor.authorGonçalo, Margarida
dc.contributor.authorMascarenhas, R
dc.contributor.authorFigueiredo, A
dc.date.accessioned2010-12-02T14:59:45Z
dc.date.available2010-12-02T14:59:45Z
dc.date.issued2010
dc.description.abstractBACKGROUND: In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been described. METHODS: We evaluated two patients with allergic contact dermatitis related to shoes manufactured in China that were contaminated by dimethylfumarate found in sachets placed inside the shoeboxes. RESULTS: Patch tests with DMF extracted from the sachets inside the shoeboxes showed positive reactions. Postitive reactions were also obtained using small fragments of the shoes and tissue of the "MouldProof" sachet. The patients were instructed to avoid the suspected shoes and were treated with topical corticosteroids. CONCLUSIONS: Contact dermatitis induced by dimethylfumarate should be suspected in appropriate cases. It is important to remember that this allergen is not included in most series for patch testing.por
dc.identifier.citationDermatol Online J. 2010 Mar 15;16(3):3.por
dc.identifier.urihttp://hdl.handle.net/10400.4/853
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectDermatite de Contacto Alérgicapor
dc.subjectAlergéniospor
dc.subjectFumaratospor
dc.subjectSapatospor
dc.titleAllergic contact dermatitis to shoes induced by dimethylfumarate: A new allergen imported from Chinapor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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