Browsing by Author "Costa, JF"
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- Amiodarone pulmonary toxicityPublication . Rodrigues, H; Belo-Oliveira, P; Costa, JF; Donato, POur patient who was on long term amiodarone treatment presented with a 10 day history of cough and dyspnea. Chest X-ray showed multiple pulmonary infiltrates. HRCT depicted patchy areas of ground glass attenuation and areas of consolidation, with a peripheral and peribronchovascular distribution, associated with dilated bronchi. The amiodarone was discontinued and the patient treated with corticosteroids.
- Endogenous endophthalmitis secondary to erysipelasPublication . Costa, JF; Marques, JP; Marques, M; Quadrado, MJA 64-year-old woman with chronic right arm lymphoedema presented with progressive and painful vision loss in the right eye following diagnosis of erysipelas in the ipsilateral arm. Visual acuity was light perception. Biomicroscopy revealed marked conjunctival injection, decreased corneal transparency and an inflammatory mass in the anterior chamber, which precluded fundoscopy. The ocular ultrasonography features were consistent with acute endophthalmitis, and the patient was admitted to the hospital. A systemic evaluation, including complete physical examination, echocardiography and blood tests, ruled out other sources of infection besides the cutaneous site. Blood cultures were positive for group A Streptococcus. A diagnosis of unilateral acute endophthalmitis due to group A Streptococcus bacteraemia secondary to erysipelas was made and successfully treated with optimal medical care, including prompt intravitreal and systemic antibiotic administration. Despite resolution of the infectious process, visual acuity did not improve.
- Giant colonic diverticulum presenting with painless rectal bleeding and diagnosed at angiography.Publication . Costa-Andrade, L; Baptista, M; Costa, JF; Caseiro-Alves, F
- Jejunal Stricture: single manifestation of Crohn’s DiseasePublication . Costa, JF; Ilharco, J; Costa, AA 60 year-old male patient was admitted to our institution referring repeated episodes of abdominal cramps and distention, weight loss, fatigue and anorexia. Abdominal radiogram showed dilatation of small bowel loops with few gas-fluid levels
- Sequential Morphological Changes in the CNV Net after Intravitreal Anti-VEGF Evaluated with OCT AngiographyPublication . Marques, JP; Costa, JF; Marques, M; Cachulo, ML; Figueira, J; Silva, RPURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avanti RTVue XR equipped with the AngioVue® software (Optovue, Calif., USA). All images were classified by two independent graders. RESULTS: Ten eyes of 10 patients, with a mean age of 72.4 ± 10.5 years, were included. CNV morphology was described as tree-like in 5 eyes, glomerular in 1 and fragmented in 4. A fibrovascular capsule surrounding the CNV net was found in 4 eyes and a feeder trunk was noticed in 6. No changes were observed at t1. Loss of peripheral capillaries, vessel fragmentation and decreased vessel density were evident in 8 eyes at t2. The CNV capillary density and the peripheral anastomosis increased in all of these at t3. Two eyes remained unchanged through the whole length of follow-up. CONCLUSIONS: Significant changes in the CNV net can be observable in OCTA at least 1 week after intravitreal anti-VEGF. The safety of frequent examinations may provide a method of gauging treatment effects.