Browsing by Author "Barcelos, A"
Now showing 1 - 6 of 6
Results Per Page
Sort Options
- Um Caso de Dor Contínua em Mulher JovemPublication . Barcelos, A; Silva, C; Reis, P; Malcata, AB; Porto, A
- Fasciíte Necrotizante e Lúpus Eritematoso SistémicoPublication . Barcelos, A; Silva, C; Pereira da Silva, JA; Malcata, AB
- Imagem em Cacho de Uva da parótida 24 horas após uma sialografiaPublication . Barcelos, A; Pereira da Silva, JA
- Radiografia das mãos: elementos típicos em artropatias comunsPublication . Barcelos, A; Nour, D; Pereira da Silva, JA
- Tofo gotoso de localização atípica em doente com múltiplos tofos gotosos infectadosPublication . Coutinho, M; Barcelos, A
- Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patientsPublication . Vaz, CC; Couto, M; Medeiros, D; Miranda, L; Costa, J; Nero, P; Barros, R; Santos, MJ; Sousa, E; Barcelos, A; Inês, LThe purpose of this study was to characterize the clinical and serological features of a large cohort of patients with antinuclear antibody (ANA) positive undifferentiated connective tissue disease (UCTD). Consecutive patients with UCTD, followed up at the Rheumatology Clinic of the participating centers, were included. Data from these patients were obtained by clinical evaluation and chart review. All patients were diagnosed as having UCTD on basis of the following criteria: positive ANA plus at least one clinical feature of connective tissue disease, but not fulfilling classification criteria for any differentiated connective tissue disease. One hundred eighty-four patients were studied (female patients-94.5%; mean age at time of evaluation-47 years). The most prevalent manifestations were arthralgia (66%), arthritis (32%), Raynaud's phenomenon (30%), sicca symptoms (30%), and leukopenia (19%). The prevalence of ANA was 100%, anti-SSA 20%, anti-dsDNA 14%, and anti-SSB 7%. Patients with anti-dsDNA/anti-Sm, anticentromere/anti-Scl70, or anti-SSA/anti-SSB antibodies more frequently presented a set of manifestations close to systemic lupus erythematosus (SLE), systemic sclerosis, or Sjögren syndrome, respectively. We analyze a large cohort of UCTD. Seventy-two percent of these UCTD patients present lupus-, scleroderma-, or Sjögren-like features but do not fulfill classification criteria and mostly present a mild disease.