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Browsing by Author "Baiardini, I"

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  • Recommendations for assessing patient-reported outcomes and health-related quality of life in patients with urticaria: a GA(2) LEN taskforce position paper
    Publication . Baiardini, I; Braido, F; Bindslev-Jensen, C; Bousquet, PJ; Brzoza, Z; Canonica, GW; Compalati, E; Fiocchi, A; Fokkens, W; Gerth van Wijk, R; Giménez-Arnau, A; Godse, K; Grattan, C; Grobb, JJ; La Grutta, S; Kalogeromitros, D; Kocaturk, E; Lombardi, C; Mota-Pinto, A; Ridolo, E; Saini, SS; Sanchez-Borges, M; Senna, GE; Terreehorst, I; Todo-Bom, A; Toubi, E; Bousquet, J; Zuberbier, T; Maurer, M
    The aim of this Global Allergy and Asthma European Network (GA(2)LEN) consensus report is to provide recommendations and suggestions for assessing patient-reported outcomes (PROs) including health-related quality of life in patients with urticaria. We recommend that PROs should be used both in clinical trials and routine practice for the evaluation of urticaria patients. We suggest that PROs should be considered as the primary outcome of future clinical trials. Two validated and disease-specific instruments for assessing PROs are available, the urticaria activity score (for symptoms) and the chronic urticaria questionnaire on quality of life CU-Q(2)oL. This latter tool, CU-Q(2)oL, is available in many languages and should be preferred, where available, over more generic instruments for assessing urticaria-specific effects on quality of life. CU-Q(2)oL is only suited for the investigation of patients with chronic spontaneous urticaria. Similar instruments for other forms of urticaria have yet to be developed and validated. Also, tools for assessing other chronic spontaneous urticaria PROs besides quality of life and symptoms are needed.
    2011Journal article Open access Show more
  • Specific recommendations for PROs and HRQoL assessment in allergic rhinitis and/or asthma: a GA(2)LEN taskforce position paper
    Publication . Braido, F; Bousquet, PJ; Brzoza, Z; Canonica, GW; Compalati, E; Fiocchi, A; Fokkens, W; Gerth van Wijk, R; La Grutta, S; Lombardi, C; Maurer, M; Mota-Pinto, A; Ridolo, E; Senna, GE; Terreehorst, I; Todo-Bom, A; Bousquet, J; Zuberbier, T; Baiardini, I
    The GA(2)LEN taskforce on Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) published in 2009 a position paper concerning PROS and HRQoL assessment in clinical trials on allergy. Because of the specificity of this topic in asthma and rhinitis, specific recommendations are needed. The aim of this position paper is to define PROs and their meaning in asthma and rhinitis research, explore the available tools to provide criteria for a proper choice, identify patient-related factor which could influence PROs assessment, define specific recommendations for assessment, analysis and results spreading, underline the unexplored areas and unmet needs. PROs assessment is gaining increasing importance, and it must be performed with a rigorous methodological procedure and using validated tools. This approach enables to better understand patient-related factors influencing clinical trials and real-life management outcomes, identify patients subgroups that can benefit from specific treatment and management plan and tailor treatment to address PROs (not only physician-defined targets) to improve asthma and rhinitis management.
    2010Journal article Open access Show more