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Browsing by Author "Baganha, MF"

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  • Avaliação da densidade mineral óssea em doentes com fibrose quística
    Publication . Cemlyn-Jones, J; Gamboa, F; Loureiro, M; Baganha, MF
    Patients with cystic fibrosis (CF) have an increasing life span and osteoporosis has become a more recognised problem in these patients. The pathogenesis of low bone mineral density (BMD) in CF seems to be multifactorial and the aim of this study was to assess the prevalence of low BMD in a group of CF outpatients and to relate the findings with the variables studied. The study included 22 patients aged between 14 and 45 years (mean age 26.3). Two of the subjects were lung transplant patients. BMD was assessed by dual-energy X-ray absorptiometry (DEXA) at the lumbar spine (LS) and femoral neck (FN). This data was correlated with serum 25-hydroxy vitamin D (25-OHD) levels, BMI and the forced expiratory volume in one second (FEV1). BMD (Z-score and T-score) ranged from 0.6 to -6 and from 0.5 to -6.7 at LS; at FN the scores ranged from 0.6 to -3.9 and from 0.6 to -4.1. The mean serum 25-OHD concentration (12,57 ng/ml) was at the low end of the normal range (10-60 ng/ml). On average patients did not present with malnutrition, however BMI ranged from 15.2 to 33.7 kg/m2. Lung function status was assessed by FEV1; 64% of patients had FEV1 below 80% and within this group four patients had a FEV1 under 40%. There was a positive correlation between low BMD and 25-OHD concentrations and also between BMD and FEV1. There was no linear correlation between BMD and BMI.
    2008Journal article Open access Show more
  • CD4 CD86 expression on experimental allergic murine model
    Publication . Pereira, C; Paiva, A; Machado, D; Henriques, A; Abrantes, M; Laranjo, M; Tavares, B; Loureiro, G; Chieira, C; Botelho, F; Baganha, MF
    2009Journal article Open access Show more
  • Ectopic thyroid in the anterior mediastinum
    Publication . Guimarães, MJ; Valente, C; Santos, L; Baganha, MF
    Ectopic thyroid is a rare condition, and its location in the anterior mediastinum is even rarer, there having been only 5 reported cases in the past 30 years. Here, we describe 2 clinical cases and present a review of the literature regarding the etiology, embryology and clinical manifestations of ectopic thyroid.
    2009Journal article Open access Show more
  • Genetic markers in chronic urticaria
    Publication . Machado, D; Pereira, C; Martinho, A; Loureiro, G; Tavares, B; Santos, P; Calado, G; Chieira, C; Baganha, MF; Pais, M
    2010Journal article Open access Show more
  • Pneumonia eosinofílica crónica idiopática: A propósito de um caso clínico
    Publication . Valente, C; André, S; Catarino, A; Loureiro, M; Baganha, MF
    The eosinophilic pneumonias are a heterogeneous group of pulmonary disorders, which may compromise only the air ways, the pulmonary parenchyma, or both, characterised by alveolar eosinophils and infiltration of pulmonary tissue, with or without peripheral blood eosinophilia. Idiopathic Chronic Eosinophilic Pneumonia (ICEP), detailed description was by Carrington in 1969, is a rare eosinophilic lung disease, of unknown aetiology, characterised by peripheral blood eosinophilia, chest radiograph infiltrates and prompt response to corticosteroid therapy. ICEP most commonly affects women of middle age and usual symptoms are cough, dyspnea, fever and weight loss. The authors present a case of ICEP in a young woman, 21 years old, non-smoker and previously healthy.
    2008Journal article Open access Show more