Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.4/96
Título: Oral squamous cell carcinoma: review of prognostic and predictive factors
Autor: Massano, J
Regateiro, FS
Januário, G
Ferreira, A
Palavras-chave: Carcinoma de Células Escamosas
Marcadores Tumorais Biológicos
Neoplasias da Boca
Data: 2006
Editora: Elsevier
Citação: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jul;102(1):67-76
Resumo: Oral squamous cell carcinoma has a remarkable incidence worldwide and a fairly onerous prognosis, encouraging further research on factors that might modify disease outcome. In this review article, the authors approach the factors that may exert influence on the prognosis and eventually guide the selection of patients for more aggressive therapies. Published scientific data was collected, selected, and grouped into 3 main clusters: patient-, tumor-, and treatment-related factors. Well established aspects are discussed, but also those less common or with only supposed usefulness. Disease staging, extracapsular dissemination, resection margin free of disease, and tumor thickness are factors with high influence on the prognosis. There has been an increasing interest in the study of tumor molecular factors, and some have been strongly correlated with the outcome, showing promising pathways for the future development of more effective prognosis systems and anticancer therapies.
URI: http://hdl.handle.net/10400.4/96
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