Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.4/1853
Título: Anti-Signal Recognition Particle Myopathy in a Geriatric Patient
Autor: Ferreira, DM
Mendes, PA
Aragão, A
Veríssimo, T
Carvalho, A
Palavras-chave: Idoso
Partícula de Reconhecimento de Sinal
Data: 2015
Citação: EJCRIM 2015;2
Resumo: Anti-signal recognition particle (SRP) myopathy is a rare idiopathic inflammatory myositis that usually affects middle-age women, and is characterized by rapidly progressive proximal and symmetrical muscle weakness, elevated creatine kinase levels, severe necrotizing immune-mediated myopathy, presence of anti-SRP autoantibodies and poor response to steroid therapy. We report a geriatric case of a previously independent patient, presenting with slow onset of proximal paraparesis, myalgia and severe gait impairment. The patient was treated with steroid and azathioprine, with laboratory and pain response but modest muscle strength improvement. The clinical presentation of this unusual patient was atypical, which hampered the correct diagnosis.
Peer review: yes
URI: http://hdl.handle.net/10400.4/1853
DOI: doi:10.12890/2015_000311
Aparece nas colecções:MED - Artigos

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